Graham Road has been re-opened to traffic.
An air ambulance is at the crash and Ambulance Victoria has confirmed they are treating one person at the scene. Major collision detectives from Melbourne are on their way.
Police have said Graham Road will be closed for up to six hours.
Police have confirmed two vehicles are involved in a collision at the corners of Curr Road and Graham Road.
Graham Road is currently closed to traffic between Scobie Road and Curr Road, and police are urging motorists to avoid the area.
Ambulance are in attendance.
More to come.