The 20-year-old has validated his status as top seed, pushing through to Sunday's Brisbane International final with another tough victory - 6-4 7-6 (7-0) against Roman Safiullin - on Saturday.
The Danish world No.8 was tested by the in-form Russian, who had slipped under the radar on his way into the final four.
Broken early in the second set by the world No.39, Rune smashed his racquet in frustration but then regrouped to break back.
He then saved break points again before executing a faultless tiebreak.
Rune turns 21 in April but has already been as high as No.4 in the world, won nearly US$8 million in prize money and made no secret of his ambitions.
Danish world No.8 Holger Rune will play for a fifth title in the Brisbane International final. (Jono Searle/AAP PHOTOS)
Rune dropped sets in both his first and second-round wins before winning tiebreaks in straight-sets wins in the quarter and semi-finals.
"It's exactly how I wanted it to be, to get the most amount of matches as possible," he said of his testing run to the final.
"It's a great challenge tomorrow to try to see where I'm at when it really matters.
"If I want to do what I want to do in Melbourne, I'm going to be under a much bigger amount of pressure if I'm going to stay on the last day on Sunday (in the Australian Open final).
"Tomorrow's a great challenge to see how I handle everything."
Rune will play the winner of Australia's Jordan Thompson, who beat Rafael Nadal on Friday night, and second seed Grigor Dimitrov.
"Yeah, but this is tennis," he said of missing the chance to meet Nadal in the final.Â
"Now I get either Thompson or Grigor. Whether it's that opponent or that opponent, that's not really up to me."
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