Beth Galetti, a senior vice president at the ecommerce company, made the announcement on Wednesday in a blog post.
The latest cuts mark the second major round of layoffs in three months after Amazon pared 14,000 jobs in October saying at the time that artificial intelligence and concerns over shifting corporate culture were to blame.
She said US-based staff would be given 90 days to look for a new role internally. Those who are unsuccessful or don't want a new job will be offered severance pay, outplacement services and health insurance benefits, she said.
"While we're making these changes, we'll also continue hiring and investing in strategic areas and functions that are critical to our future," Galetti said.
The layoffs are Amazon's biggest since 2023, when the company cut 27,000 jobs.
Amazon's workforce doubled during the COVID-19 pandemic as millions stayed home and boosted online spending. But in the following years, big tech and retail companies cut thousands of jobs to bring spending back in line.
The company has been investing in robotics at its warehouses to speed up packaging and deliveries for its e-commerce segment, reduce the reliance on human labour and cutting costs.
Hiring has stagnated in the US and in December, America added a meagre 50,000 jobs, nearly unchanged from a downwardly revised figure of 56,000 in November.
Labor data points to a reluctance by businesses to add workers even as US economic growth has picked up.
Many companies hired aggressively after the pandemic and no longer need to fill more jobs. Others have held back due to widespread uncertainty caused by President Donald Trump's shifting tariff policies, elevated inflation, and the spread of artificial intelligence, which could alter or even replace some jobs.
with Reuters
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