Kyiv Mayor Vitali Klitschko said on the Telegram messaging app there were several explosions in the Ukrainian capital after air defence systems were engaged in repelling the attack.
Ukraine air defence forces destroyed about a dozen Russia-launched missiles over Kyiv and in the vicinity of the capital, Serhiy Popko, head of Kyiv's military administration, said on Telegram.
For the third pre-dawn morning this week, all of Ukraine is under an air alert and has been advised to seek shelter. Russia continues to indiscriminately launch drones and missiles with no regard for millions of civilians, violating international law.— Ambassador Bridget A. Brink (@USAmbKyiv) March 24, 2024
Preliminary information showed no casualties or major damage as a result of the attacks, he said.
Russia has been pounding Ukraine for days in attacks portrayed by Moscow as revenge for Ukrainian attacks during its recent presidential election.
"For the third pre-dawn morning this week, all of Ukraine is under an air alert and has been advised to seek shelter," US Ambassador Bridget Brink posted on X early on Sunday.
"Russia continues to indiscriminately launch drones and missiles with no regard for millions of civilians, violating international law."
Russia's defence ministry did not immediately reply to a request for comment.
In major attack on Lviv, Russian missiles were flying close to the border with Poland, Ukraine's Telegram news outlets reported.
"Polish and allied aircraft have been activated, which may result in increased noise levels, especially in the southeastern part of the country," Poland's armed forces said on X.
Lviv Mayor Andriy Sadovyi said on Telegram there were no attacks on the city but some 20 missiles and seven attack drones had been launched against the broader Lviv region, targeting "critical infrastructure".
It comes as Russian air defence systems shot down more than 10 missiles over the Crimean port of Sevastopol late on Saturday, a Russian-installed official said, forcing transport disruptions on the peninsula that Moscow annexed from Ukraine.
"Our military is repelling a massive attack on Sevastopol," Mikhail Razvozhayev, the Russia-installed governor of Sevastopol, said on the Telegram messaging app.
Preliminary information showed more than 10 missiles had been shot down, he said.
One woman suffered a shrapnel injury and infrastructure was damaged, including an office building and a gas line, he said.
The Moscow-installed transport administration of the region said that the sea and road transport linking Russia's mainland with the Crimean Peninsula, which Moscow annexed in 2014 from Ukraine, was suspended for several hours.