The strong performance by President Maia Sandu's Party of Action and Solidarity against the Patriotic Bloc will be a relief for the government and its European partners who had accused Moscow of seeking to influence the outcome.
Polls leading up to the election put PAS and Patriotic Bloc neck-and-neck with neither likely to get close to a majority. The near-final tally by Moldova's electoral commission allows the government to push for its goal of EU membership by 2030.
It also spares Moldova the political horse trading that had threatened to invite more instability following what officials described as a Russian campaign to disrupt the vote and derail Chisinau's course toward Europe.
Moscow has denied meddling in Moldova.
With nearly all votes counted, PAS won 50.1 per cent versus 24.2 per cent for the Patriotic Bloc, which had sought to steer Moldova closer to Moscow.
The build-up to an election that PAS leaders called the most consequential since Moldova's independence from the Soviet Union in 1991 was marred by accusations of foul play by both sides up to and on the day of polling.
Sandu's government warned Moldovans that Russia had attempted to sway the vote through widespread disinformation and vote-buying.
Stanislav Secrieru, Sandu's national security adviser, said election infrastructure and government websites had come under cyber attack, and that fake bomb threats were called in to polling stations in Moldova and abroad.
On Sunday, Patriotic Bloc co-leader Igor Dodon, a former Moldovan president, called for protests on Monday in front of parliament, claiming that Sandu was planning to annul the vote. He did not provide evidence.
Authorities, which had also warned of Russian-backed attempts to stir unrest after the vote, will watch closely to see if Dodon follows through on the threat, and what crowds he can command if he does.
In reaction to PAS' victory, French President Emmanuel Macron said France stands beside Moldova regarding its European aspirations.
"France stands beside Moldova in its European aspirations and its desire for freedom and sovereignty," he wrote on X.
European Commission president Ursula von der Leyen said Moldova had made its choice clear: "Europe. Democracy. Freedom."
Moldova - with a population of 2.4 million people that has been buffeted by the war in neighbouring Ukraine, alleged Russian interference and energy shortages - has long vacillated between Russia and Europe.
The Patriotic Bloc and other opposition groups had sought to tap into voter anger over economic pain and the slow pace of reforms - grievances worsened by what officials say has been widespread disinformation.
But the electoral performance by PAS suggests its platform of European integration and breaking with Russia resonates among wide swathes of voters.
