It was the fifth Ukrainian attack on the pipeline which supplies Russian oil to Hungary and Slovakia, according to Reuters calculations.
Hungary and Slovakia continue to buy energy supplies from Russia, even after other European Union countries cut ties following its invasion of Ukraine in 2022.
Ukrainian media said remote-controlled explosives were used in the attack.
Slovak pipeline operator and Hungarian oil and gas company said later on Wednesday that oil supplies through Druzhba were running as normal.
Ukraine attacked the pipeline once in March, twice in August and once in September this year.
Ukraine says its strikes on energy targets, in response to Russia's continued attacks on Ukraine, aim to undermine the Russian war effort.
Ukraine and its European allies accused Russian President Vladimir Putin on Wednesday of feigning interest in peace efforts after seemingly unproductive talks at the Kremlin.
The Russian leader "should end the bluster and the bloodshed and be ready to come to the table and to support a just and lasting peace," UK Foreign Secretary Yvette Cooper said.
Ukrainian Foreign Minister Andrii Sybiha urged Putin to "stop wasting the world's time".
The remarks reflect the high tensions and gaping gulf that remain between Russia on one side and Ukraine and its European allies on the other over how to end a war that the Kremlin started when it invaded its neighbour nearly four years ago.
On Wednesday, the Kremlin spokesman said he would not discuss the substance of the talks but rejected any suggestion that Putin had rejected a US peace plan on Ukraine.
"The more quietly these talks are conducted, the more productive they are," Kremlin spokesman Dmitry Peskov said on Wednesday, after a long meeting between Putin and US negotiators in Moscow.
"We will adhere to this principle, and we hope that our US counterparts will also adhere to it," Peskov said, according to the TASS news agency.
"We are ready to meet as often as necessary to reach a peace settlement," he said.
Where the peace talks go from here depends largely on whether US President Donald Trump's administration decides to increase the pressure on Russia or on Ukraine to make concessions.
After the talks, Yuri Ushakov, a senior adviser to Putin, told reporters that "so far, a compromise hasn't been found" on the issue of territory, without which, he said, the Kremlin sees "no resolution to the crisis".
with AP and DPA