Speaking at CNBC's Invest in America Forum, Infantino said it is important that Iran takes part in the World Cup starting in June even though its participation has been in doubt since the US and Israel launched airstrikes on the country.
"The Iranian team is coming for sure, yes," Infantino said. "We hope that by then, of course, the situation will be a peaceful situation. As I said, that would definitely help. But Iran has to come. Of course, they represent their people. They have qualified. The players want to play."
Infantino met with the Iranian national team in Antalya, Turkey, two weeks ago and said on Wednesday he was impressed.
"I went to see them. They are actually quite a good team as well," Infantino said. "And they really want to play and they should play. Sports should be outside of politics now."
Infantino acknowledged it was not always possible to achieve the separation of sports and politics.
"OK we don't live on the moon, we live on planet Earth," Infantino said. "But you know if there is nobody else that believes in building bridges and in keeping them, you know, intact and together, well we are doing that job."
The United States will co-host the World Cup with Canada and Mexico.
Iran are scheduled to play two group-stage games in Inglewood, California, and one in Seattle.
The war has raised doubts about Iran's participation in the World Cup. There have been conflicting public comments from Iranian government and soccer officials. US President Donald Trump discouraged the Iranian team from attending the tournament, citing safety concerns.
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