McQualter led the Tigers to a commendable 7-6 record as caretaker coach following Damien Hardwick's mid-season resignation in 2023.
Buoyed by those results, McQualter threw his hat in the ring for the full-time job, but missed out after Richmond opted to go for Adem Yze instead.
McQualter ended up landing the top job at West Coast at the end of 2025, but to date there have only been five wins to show from 42 games in charge of the rebuilding Eagles.
The record against Richmond sits at 0-3 and McQualter is determined to turn that around this week on a rare visit to the MCG.
"I'm sick of losing to them, for sure," McQualter said on Thursday.
"It's like three times in a row. I want to beat them."
West Coast were hot favourites to beat injury-hit Richmond in round eight in Perth, only for the Tigers to buck the odds with an 11-point win.
Richmond also beat the Eagles by 49 points at Optus Stadium last year, and two points in last season's clash in Melbourne.
Richmond (2-17) are on the bottom of the table, while West Coast (4-15) are only marginally above them.
There is pressure on both clubs to show their extensive rebuilds are on track, meaning the result of Sunday's game is significant despite finals not being in the equation.
West Coast's list has swelled to 51 players this season due to AFL concessions and mid-season injury-replacement pick-ups.
It means there are up to 15 uncontracted players whose futures will be decided in the coming weeks.
Premiership defender Tom Cole, ruckman Matt Flynn, Noah Long, Jacob Newton, Clay Hall, Fred Rodriguez, Harry Barnett, Harvey Johnston, Tyler Brockman and Malakai Champion are among those coming out of contract.
"They (decisions on uncontracted players) are definitely not already made," McQualter said.
"There's definitely guys that are still up in the air. That's what happens at every time, every year, at every club.
"It's not just going to be judged on the last four games. I think that'd be unfair, but you certainly try and get an understanding of what we think people's ceilings are and where they can get to as players.
"There's going to be some unlucky plays at the end of our season that miss out a contract."
McQualter confirmed he had spoken to the AFL about the way Harley Reid has been umpired this season, saying it was a "respectful, two-way" conversation that will remain private.